Thermoresponsive Swelling of Photoacoustic Single-Chain Nanoparticles

Thümmler, J.F. et al., Chemical Communications, 2023, DOI https://doi.org/10.1039/D3CC03851C

NIR-fluorescent LCST-type single-chain nanoparticles (SCNPs) change their photophysical behaviour upon heating, caused by depletion of water from the swollen SCNP interiors. This thermoresponsive effect leads to a fluctuating photoacoustic (PA) signal which can be used as a contrast mechanism for PA imaging. Published with a permission of the Royal Society of Chemistry 2023.