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3. Juni 2020

Probing Polymer Chain Conformation and Fibril Formation of Peptide Conjugates.

Evgrafova, Z., et al. ChemPhysChem2019,20 (2), 236-240,DOI: https://doi.org/10.1002/cphc.201800867.

Covalent conjugates between a synthetic polymer and a peptide hormone were used to probe the molecular extension of these macromolecules. NMR spectroscopy of 15N labeled parathyroid hormone (PTH) was employed to visualize the shroud-like polymer conformation of the conjugated chimeras. Reproduced by permission. Copyright © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.