Funtan, S., et al. Organic Materials 2020, 2, 116-128,DOI: https://doi.org/10.1055/s-0040-1702149.
Elastin-like polypeptides (ELPs) are well known for their elastic and thermoresponsive behaviors. Here, the synthesis of ELPs of varying chain lengths and their coupling to a mechanoresponsive catalyst are reported. Mechanochemical activation of the synthesized catalysts by an external applied force, showed conversions of the copper(I)-catalyzed alkyne-azide “click” reaction (CuAAC) up to 5.6% with an increasing chain length of the peptide. Reproduced with permission. Copyright 2020© Georg Thieme Verlag KG, Germany.